in force 2022-03-01
02008R1272-20211001 → 02008R1272-20220301
Amended by Regulation (EU) 2020/1182 32020R1182
detected 2026-08-13
1 provision touched — 1 substantive, 0 date-only, 1 disputed · 1 change without an explanation
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MODIFIED +16,726 −6,328 Annex VI Harmonised classification and labelling for certain hazardous substances§
applies from: unchanged
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02008R1272-20211001 → 02008R1272-20220301
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ANNEX VI
Harmonised classification and labelling for certain hazardous substances
Part 1 of this Annex provides an introduction to the list of harmonised classification and labelling, including information listed for each entry and related classifications and hazard statements in Table 3.
… 1,819 unchanged lines …
Acute Tox. 4 * H312
H302 GHS07
Wng H312
H302 007-004-00-1 nitric acid … % 231-714-2 7697-37-2 Ox. Liq. 2 H302 007-004-00-1 nitric acid …% [C > 70 %] 231-714-2 7697-37-2 Ox. Liq. 2
Acute Tox. 1
Skin Corr. 1A H272
H330
H314 GHS03
GHS06
GHS05
Dgr H272
H314 EUH071 Skin Corr. 1A; H314: C ≥ 20 %
Skin Corr. 1B; H314: 5 % ≤ C < 20 %
Ox. Liq. 2; H272: C ≥ 99 %
Ox. Liq. 3; H272: 99 % > C ≥ 65 % B H330
H314 EUH071 Ox. Liq. 2; H272: C ≥ 99 %
Ox. Liq. 3; H272: 70 % ≤ C < 99 % B
007-006-00-2 ethyl nitrite 203-722-6 109-95-5 Flam. Gas 1
Press. Gas
Acute Tox. 4 *
… 315 unchanged lines …
GHS07
Dgr H312
H302
H314 008-001-00-8 oxygen 231-956-9 7782-44-7 Ox. Gas 1 H314 007-030-00-3 nitric acid …% [C ≤ 70 %] 231-714-2 7697-37-2. Ox. Liq. 3
Acute Tox. 3
Skin Corr. 1A H272
H331
H314 GHS03
GHS06
GHS05
Dgr H272
H331
H314 EUH071 Ox. Liq. 3; H272: C ≥ 65 %
inhalation: ATE = 2,65 mg/L (vapours)
Skin Corr. 1A; H314: C ≥ 20 %
Skin Corr. 1B; H314: 5 % ≤ C < 20 % B
008-001-00-8 oxygen 231-956-9 7782-44-7 Ox. Gas 1
Press. Gas H270 GHS03
GHS04
Dgr H270 U
… 407 unchanged lines …
GHS09
Dgr H351
H360D *** H302
H411 014-018-00-1 octamethylcyclotetrasiloxane 209-136-7 556-67-2 Repr. 2
Aquatic Chronic 4 H361f *** H413 GHS08
Wng H361f *** H413 014-019-00-7 reaction mass of: 4-[[bis-(4-fluorophenyl)methylsilyl]methyl]-4H-1,2,4-triazole; H411 014-018-00-1 octamethylcyclotetrasiloxane;
[D4] 209-136-7 556-67-2 Repr. 2
Aquatic Chronic 1 H361f ***
H410 GHS08
GHS09
Wng H361f ***
H410 M = 10 014-019-00-7 reaction mass of: 4-[[bis-(4-fluorophenyl)methylsilyl]methyl]-4H-1,2,4-triazole;
1-[[bis-(4-fluorophenyl)methylsilyl]methyl]-1H-1,2,4-triazole 403-250-2 — Carc. 2
Repr. 1B
Acute Tox. 4 *
… 129 unchanged lines …
Dgr H350i A
014-047-00-X glass microfibres of representative composition; [Calcium-aluminium-silicate fibres with random orientation with the following composition (% given by weight): SiO2 55,0-60,0 %, Al2O3 4,0-7,0 %, B2O3 8,0-11,0 %, ZrO2 0,0-4,0 %, Na2O 9,5-13,5 %, K2O 0,0-4,0 %, CaO 1,0-5,0 %, MgO 0,0-2,0 %, Fe2O3 < 0,2 %, ZnO 2,0-5,0 %, BaO 3,0-6,0 %, F2 < 1,0 %. Process: typically produced by flame attenuation and rotary process. (Additional individual elements may be present at low levels; the process list does not preclude innovation).] — — Carc. 2 H351 (inhalation) GHS08
Wng H351 (inhalation) A
015-001-00-1 white phosphorus 231-768-7 12185-10-3 Pyr. Sol. 1 014-048-00-5 silicon carbide fibres (with diameter < 3 μm, length > 5 μm and aspect ratio ≥ 3:1) 206-991-8 409-21-2
308076-74-6 Carc. 1B H350i GHS08
Dgr H350i 014-049-00-0 trimethoxyvinylsilane; trimethoxy(vinyl)silane 220-449-8 2768-02-7 Skin Sens. 1B H317 GHS07
Wng H317 014-050-00-6 tris(2-methoxyethoxy)vinylsilane;
6-(2-methoxyethoxy)-6-vinyl-2,5,7,10-tetraoxa-6-silaundecane 213-934-0 1067-53-4 Repr. 1B H360FD GHS08
Dgr H360FD 015-001-00-1 white phosphorus 231-768-7 12185-10-3 Pyr. Sol. 1
Acute Tox. 2 *
Acute Tox. 2 *
Skin Corr. 1A
… 1,288 unchanged lines …
GHS09
Wng H302
H410 M = 10 015-134-00-5 pirimiphos-methyl (ISO);
O-(2-diethylamino-6-methylpyrimidin-4-yl) O, O-dimethyl phosphorothioate 249-528-5 29232-93-7 Acute Tox. 4 * O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl phosphorothioate 249-528-5 29232-93-7 Acute Tox. 4
STOT RE 1
Aquatic Acute 1
Aquatic Chronic 1 H302
H372 (nervous system)
H400
H410 GHS07
GHS08
GHS09
Wng H302
H410 015-135-00-0 profenofos (ISO)O-(4-bromo-2-chlorophenyl) O-ethyl S-propyl phosphorothioate; 255-255-2 41198-08-7 Acute Tox. 4 * Dgr H302
H372 (nervous system)
H410 oral: ATE = 1414 mg/kg bw
M = 1000
M = 1000 015-135-00-0 profenofos (ISO)O-(4-bromo-2-chlorophenyl) O-ethyl S-propyl phosphorothioate; 255-255-2 41198-08-7 Acute Tox. 4 *
Acute Tox. 4 *
Acute Tox. 4 *
Aquatic Acute 1
… 395 unchanged lines …
H317
H412 015-181-00-1 phosphine 232-260-8 7803-51-2 Flam. Gas 1
Press. Gas
Acute Tox. 2 * Acute Tox. 1
Skin Corr. 1B
Aquatic Acute 1 H220
H330
H314
H400 GHS02
GHS04
GHS06
GHS05
GHS09
Dgr H220
H330
H314
H400 U H400 inhalation:
ATE = 10 ppmV (gases) U
015-182-00-7 tetrapropan-2-yl (dichloromethanediyl)bis(phosphonate) 430-630-5 10596-22-2 Acute Tox. 4 *
Eye Irrit. 2
Skin Sens. 1 H302
… 752 unchanged lines …
Dgr H302
H314
H317
H412 017-001-00-7 chlorine 231-959-5 7782-50-5 Ox. Gas 1 H412 016-098-00-3 dimethyl disulphide 210-871-0 624-92-0 Flam. Liq. 2
Acute Tox. 3
Acute Tox. 3
STOT SE 3
STOT SE 1
Eye Irrit. 2
Skin Sens. 1
Aquatic Acute 1
Aquatic Chronic 1 H225
H331
H301
H336
H370 (upper respiratory tract, inhalation)
H319
H317
H400
H410 GHS02
GHS06
GHS08
GHS09
Dgr H225
H331
H301
H336
H370 (upper respiratory tract, inhalation)
H319
H317
H410 inhalation: ATE = 5 mg/L (vapours)
oral: ATE = 190 mg/kg bw
M = 1
M = 10 017-001-00-7 chlorine 231-959-5 7782-50-5 Ox. Gas 1
Press. Gas
Acute Tox. 3 *
Eye Irrit. 2
… 2,369 unchanged lines …
GHS09
Dgr H302
H318
H410 M = 10 030-001-00-1 zinc powder — zinc dust (pyrophoric) 231-175-3 7440-66-6 Water-react. 1 H410 M = 10 029-024-00-X granulated copper;
[particle length: from 0,9 mm to 6,0 mm; particle width: from 0,494 to 0,949 mm] 231-159-6 7440-50-8 Aquatic Chronic 2 H411 GHS09 H411 029-025-00-5 bis(N-hydroxy-N-nitrosocyclohexylaminato-O,O’)copper;
bis(N-cyclohexyl-diazenium-dioxy)-copper;
[Cu-HDO] 239-703-4 312600-89-8
15627-09-5 Flam. Sol. 1
Acute Tox. 4
STOT RE 2
Eye Dam. 1
Aquatic Acute 1
Aquatic Chronic 1 H228
H302
H373 (liver)
H318
H400
H410 GHS02
GHS07
GHS08
GHS05
GHS09
Dgr H228
H302
H373(liver)
H318
H410 oral: ATE = 360 mg/kg bw
M = 1
M = 1 030-001-00-1 zinc powder — zinc dust (pyrophoric) 231-175-3 7440-66-6 Water-react. 1
Pyr. Sol. 1
Aquatic Acute 1
Aquatic Chronic 1 H260
… 948 unchanged lines …
H413 GHS08
GHS07
Dgr H372 ** H315
H413 050-021-00-4 dichlorodioctyl stannane 222-583-2 3542-36-7 Acute Tox. 3 * H413 050-021-00-4 dichlorodioctylstannane 222-583-2 3542-36-7 Repr. 1B
Acute Tox. 2
STOT RE 1
Aquatic Chronic 3 H331
H372**
H412 GHS06
GHS08
Dgr H331
H372**
H412 050-022-00-X dibutyltin dichloride; Aquatic Chronic 3 H360D
H330
H372 **
H412 GHS08
GHS06
Dgr H360D
H330
H372 **
H412 Repr. 1B; H360 D: C ≥ 0,03 %
inhalation: ATE = 0,098 mg/L (dusts or mists) 050-022-00-X dibutyltin dichloride;
(DBTC) 211-670-0 683-18-1 Muta. 2
Repr. 1B
Acute Tox. 2 *
… 56 unchanged lines …
H317
H410 050-025-00-6 trichloromethylstannane 213-608-8 993-16-8 Repr. 2 H361d GHS08
Wng H361d 050-026-00-1 2-ethylhexyl 10-ethyl-4-[[2-[(2-ethylhexyl)oxy]-2-oxoethyl]thio]-4-methyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate 260-828-5 57583-34-3 Repr. 2 H361d GHS08
Wng H361d 050-027-00-7 2-ethylhexyl 10-ethyl-4,4-dioctyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate 239-622-4 15571-58-1 Repr. 1B H360D GHS08
Dgr H360D 050-028-00-2 2-ethylhexyl 10-ethyl-4,4-dimethyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate 260-829-0 57583-35-4 Repr. 2 Wng H361d 050-027-00-7 2-ethylhexyl 10-ethyl-4,4-dioctyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate; [DOTE] 239-622-4 15571-58-1 Repr. 1B
STOT RE 1
Aquatic Acute 1
Aquatic Chronic 1 H360D
H372 (immune system)
H400
H410 GHS08
GHS09
Dgr H360D
H372 (immune system)
H410 050-028-00-2 2-ethylhexyl 10-ethyl-4,4-dimethyl-7-oxo-8-oxa-3,5-dithia-4-stannatetradecanoate 260-829-0 57583-35-4 Repr. 2
Acute Tox. 4
STOT RE 1
Skin Sens. 1A H361d
… 31 unchanged lines …
H372 (immune system) GHS08
Dgr H341
H360FD
H372 (immune system) 050-031-00-9 dioctyltin dilaurate; [1]
stannane, dioctyl-, bis(coco acyloxy) derivs. [2] 222-883-3 [1] 293-901-5 [2] 3648-18-8 [1] 91648-39-4 [2] Repr. 1B
STOT RE 1 H360D
H372 (immune system) GHS08
Dgr H360D
H372 (immune system) 051-001-00-8 antimony trichloride 233-047-2 10025-91-9 Skin Corr. 1B
Aquatic Chronic 2 H314
H411 GHS05
… 769 unchanged lines …
GHS09
Wng H302
H373**
H411 082-013-00-1 lead powder;
[particle diameter < 1 mm] 231-100-4 7439-92-1 Repr. 1A
Lact. H360FD
H362 GHS08
Dgr H360FD
H362 Repr. 1A; H360D: C ≥ 0,03 % 082-014-00-7 lead massive: H411 082-013-00-1 lead powder; [particle diameter < 1 mm] 231-100-4 7439-92-1 Repr. 1A
Lact.
Aquatic Acute 1
Aquatic Chronic 1 H360FD
H362
H400
H410 GHS08
GHS09
Dgr H360FD H362
H410 Repr. 1A; H360D: C ≥ 0,03 %
M = 1
M = 10 082-014-00-7 lead massive:
[particle diameter ≥ 1 mm] 231-100-4 7439-92-1 Repr. 1A
Lact. H360FD
H362 GHS08
… 945 unchanged lines …
Muta. 2 H350
H341 GHS08
Dgr H350
H341 602-001-00-7 chloromethane; H341 601-092-00-0 dibenzo[def,p]chrysene;
dibenzo[a,l]pyrene 205-886-4 191-30-0 Carc. 1B
Muta. 2 H350
H341 GHS08
Dgr H350
H341 Carc. 1B; H350: C ≥ 0,001 % 602-001-00-7 chloromethane;
methyl chloride 200-817-4 74-87-3 Flam. Gas 1
Press. Gas
Carc. 2
… 1,458 unchanged lines …
Wng H332
H312
H319 603-014-00-0 2-butoxyethanol;
ethyleneglycol monobutyl ether;
butyl cellosolve 203-905-0 111-76-2 Acute Tox. 4 *
Acute Tox. 4 *
Acute Tox. 4 *
Eye Irrit. 2
Skin Irrit. 2 H332
H312 ethylene glycol monobutyl ether 203-905-0 111-76-2 Acute Tox. 4*
Acute Tox. 4
Skin Irrit. 2
Eye Irrit. 2 H332
H302
H319
H315 GHS07 H315
H319 GHS07
Wng H332
H312
H302
H319
H315 603-015-00-6 allyl alcohol 203-470-7 107-18-6 Flam. Liq. 2 H315
H319 oral: ATE = 1200 mg/kg bw 603-015-00-6 allyl alcohol 203-470-7 107-18-6 Flam. Liq. 2
Acute Tox. 3 *
Acute Tox. 3 *
Acute Tox. 3 *
… 564 unchanged lines …
H336 GHS02
GHS07
Wng H226
H336 603-065-00-9 resorcinol diglycidyl ether;1,3-bis(2,3-epoxypropoxy)benzene 202-987-5 101-90-6 Carc. 2 H336 603-065-00-9 m-bis(2,3-epoxypropoxy)benzene;
resorcinol diglycidyl ether 202-987-5 101-90-6 Carc. 1B
Muta. 2
Acute Tox. 4 * Acute Tox. 4 * Acute Tox. 3
Acute Tox. 4
Skin Irrit. 2
Eye Irrit. 2
Skin Irrit. 2
Skin Sens. 1
Aquatic Chronic 3 H351 Aquatic Chronic 3 H350
H341
H312 H311
H302
H315
H319
H315
H317
H412 GHS08
GHS07
Wng H351 GHS06
Dgr H350
H341
H312 H311
H302
H315
H319
H315
H317
H412 603-066-00-4 1,2-epoxy-4-epoxyethylcyclohexane; 4-vinylcyclohexene diepoxide 203-437-7 106-87-6 Carc. 2 H412 dermal: ATE = 300 mg/kg bw oral: ATE = 500 mg/kg bw 603-066-00-4 1,2-epoxy-4-epoxyethylcyclohexane; 4-vinylcyclohexene diepoxide 203-437-7 106-87-6 Carc. 2
Acute Tox. 3 * Acute Tox. 3 *
Acute Tox. 3 * H351
H331
… 992 unchanged lines …
126-90-9 [2]
126-91-0 [3] Skin Sens. 1B H317 GHS07
Wng H317 603-236-00-8 ethanol, 2,2’-iminobis-, N-(C13-15-branched and linear alkyl) derivs. 308-208-6 97925-95-6 Repr. 1B H360D GHS08
Dgr H360D 604-001-00-2 phenol; carbolic acid; monohydroxybenzene; phenylalcohol 203-632-7 108-95-2 Muta. 2 Dgr H360D 603-237-00-3 ipconazole (ISO);
(1RS,2SR,5RS;1RS,2SR,5SR)-2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol - 125225-28-7
115850-69-6
115937-89-8 Repr. 1B
Acute Tox. 4
STOT RE 2
Aquatic Chronic 1 H360D
H302
H373 (eyes, skin, liver)
H410 GHS08
GHS07
GHS09
Dgr H360D
H302
H373 (eyes, skin, liver)
H410 oral: ATE = 500 mg/kg bw
M = 100 603-238-00-9 bis(2-(2-methoxyethoxy)ethyl)ether; tetraglyme 205-594-7 143-24-8 Repr. 1B H360FD GHS08
Dgr H360FD 603-239-00-4 paclobutrazol (ISO);
(2RS,3RS)-1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol - 76738-62-0 Repr. 2
Acute Tox. 4
Acute Tox. 4
Eye Irrit. 2
Aquatic Acute 1
Aquatic Chronic 1 H361d
H332
H302
H319
H400
H410 GHS08
GHS07
GHS09
Wng H361d
H332
H302
H319
H410 inhalation: ATE = 3,13 mg/L (dusts or mists)
oral: ATE = 490 mg/kg bw
M = 10
M = 10 603-240-00-X 2,2-bis(bromomethyl)propane-1,3-diol 221-967-7 3296-90-0 Carc. 1B
Muta. 1B H350
H340 GHS08
Dgr H350
H340 603-241-00-5 geraniol;
(2E)-3,7-dimethylocta-2,6-dien-1-ol 203-377-1 106-24-1 Skin Sens. 1 H317 GHS07
Wng H317 604-001-00-2 phenol; carbolic acid; monohydroxybenzene; phenylalcohol 203-632-7 108-95-2 Muta. 2
Acute Tox. 3 * Acute Tox. 3 *
Acute Tox. 3 * STOT RE 2 *
Skin Corr. 1B H341
… 1,135 unchanged lines …
257-187-9 [3] 130066-44-3 [1]
31906-04-4 [2]
51414-25-6 [3] Skin Sens. 1A H317 GHS07
Wng H317 606-001-00-8 acetone; propan-2-one; propanone 200-662-2 67-64-1 Flam. Liq. 2 Wng H317 605-041-00-3 2-(4-tert-butylbenzyl)propionaldehyde 201-289-8 80-54-6 Repr. 1B H360Fd GHS08
Dgr H360Fd 606-001-00-8 acetone; propan-2-one; propanone 200-662-2 67-64-1 Flam. Liq. 2
Eye Irrit. 2
STOT SE 3 H225
H319
… 2,415 unchanged lines …
H411 GHS07
GHS09
Wng H317
H411 607-177-00-9 tribenuron-methyl (ISO); 2-[4-methoxy-6-methyl-1,3,5-triazin-2-yl(methyl)carbamoylsulfamoyl]benzoic acid methyl ester; methyl 2-(3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3methylureidosulfonyl)benzoate 401-190-1 101200-48-0 Skin Sens. 1 H411 607-177-00-9 tribenuron-methyl (ISO);
methyl 2-[N-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-N-methylcarbamoylsulfamoyl]benzoate 401-190-1 101200-48-0 STOT RE 2
Skin Sens. 1
Aquatic Acute 1
Aquatic Chronic 1 H317 Aquatic Chronic 1 H373
H317
H400
H410 GHS07 H410 GHS08
GHS07
GHS09
Wng H317
H410 M = 100 607-178-00-4 methyl α-((4,6-dimethoxypyrimidin-2-yl)ureidosulphonyl)-o-toluate 401-340-6 83055-99-6 Skin Sens. 1 Wng H373
H317
H410 M = 100
M = 100 607-178-00-4 methyl α-((4,6-dimethoxypyrimidin-2-yl)ureidosulphonyl)-o-toluate 401-340-6 83055-99-6 Skin Sens. 1
Aquatic Chronic 2 H317
H411 GHS07
GHS09
… 535 unchanged lines …
GHS09
Dgr H330
H300
H410 607-255-00-2 fluroxypyr (ISO);4-amino-3,5-dichloro-6-fluoro-2-pyridyloxyacetic acid — 69377-81-7 Aquatic Chronic 3 H412 — H412 607-256-00-8 azoxystrobin (ISO); methyl (E)-2-{2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]phenyl}-3-methoxyacrylate — 131860-33-8 Acute Tox. 3 * Aquatic Acute 1 H410 607-255-00-2 fluroxypyr (ISO);4-amino-3,5-dichloro-6-fluoro-2-pyridyloxyacetic acid — 69377-81-7 Aquatic Chronic 3 H412 — H412 607-256-00-8 azoxystrobin (ISO);
methyl (E)-2-{2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]phenyl}-3-methoxyacrylate - 131860-33-8 Acute Tox. 3
Aquatic Acute 1
Aquatic Chronic 1 H331
H400
H410 GHS06
GHS09
Dgr H331
H410 607-257-00-3 isopropyl propionate 211-300-8 637-78-5 Flam. Liq. 2 H225 GHS02 H410 inhalation:
ATE = 0,7 mg/L (dusts or mists)
M = 10
M = 10 607-257-00-3 isopropyl propionate 211-300-8 637-78-5 Flam. Liq. 2 H225 GHS02
Dgr H225 607-258-00-9 dodecyl 3-(2-(3-benzyl-4-ethoxy-2,5-dioxoimidazolidin-1-yl)-3-(4-methoxybenzoyl)acetamido)-4-chlorobenzoate 403-990-6 70950-45-7 Aquatic Chronic 4 H413 — H413 607-259-00-4 methyl 2R,3S-(-)-3-(4-methoxyphenyl)oxiranecarboxylate 404-130-2 105560-93-8 Eye Dam. 1
Skin Sens. 1
Aquatic Chronic 3 H318
… 262 unchanged lines …
GHS06
Dgr H330
H302
H314 STOT SE 3; H335: C ≥ 5 % 607-314-00-2 ethofumesate (ISO); (±)-2-ethoxy-2,3-dihydro-3,3-dimethylbenzofuran-5-ylmethanesulfonate 247-525-3 26225-79-6 Aquatic Chronic 2 H411 GHS09 H411 607-315-00-8 glyphosate (ISO); N-(phosphonomethyl)glycine 213-997-4 1071-83-6 Eye Dam. 1 H314 STOT SE 3; H335: C ≥ 5 % 607-314-00-2 ethofumesate (ISO);
(RS)-2-ethoxy-2,3-dihydro-3,3-dimethylbenzofuran-5-yl methanesulfonate 247-525-3 26225-79-6 Aquatic Acute 1
Aquatic Chronic 1 H400
H410 GHS09
Wng H410 M = 1
M = 1 607-315-00-8 glyphosate (ISO); N-(phosphonomethyl)glycine 213-997-4 1071-83-6 Eye Dam. 1
Aquatic Chronic 2 H318
H411 GHS05
GHS09
… 2,160 unchanged lines …
Wng H332
H373 (inhalation) inhalation:
ATE = 1,5 mg/l (dusts or mists) 607-737-00-2 diisohexyl phthalate 276-090-2 71850-09-4 Repr. 1B H360FD GHS08
Dgr H360FD 608-001-00-3 acetonitrile; cyanomethane 200-835-2 75-05-8 Flam. Liq. 2 Dgr H360FD 607-738-00-8 MCPA-thioethyl (ISO);
S-ethyl (4-chloro-2-methylphenoxy)ethanethioate; S-ethyl 4-chloro-o-tolyloxythioacetate 246-831-4 25319-90-8 Acute Tox. 4
STOT RE. 2
Aquatic Acute 1 Aquatic Chronic 1 H302
H373 (liver)
H400
H410 GHS07
GHS08
GHS09
Wng H302
H373 (liver)
H410 oral: ATE = 450 mg/kg bw
M = 10
M = 10 607-740-00-9 diisooctyl phthalate 248-523-5 27554-26-3 Repr. 1B H360FD GHS08
Dgr H360FD 607-741-00-4 4-{[(6-chloropyridin-3-yl)methyl](2,2-difluoroethyl)amino}furan-2(5H)-one; flupyradifurone — 951659-40-8 Acute Tox. 4
STOT RE 2
Aquatic Acute 1
Aquatic Chronic 1 H302
H373 (muscle)
H400
H410 GHS07
GHS08
GHS09
Wng H302
H373 (muscle)
H410 oral: ATE = 500 mg/kg bw
M = 10
M = 10 607-742-00-X thiencarbazone-methyl (ISO);
methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carbonylsulfamoyl]-5- methylthiophene-3-carboxylate — 317815-83-1 Aquatic Acute 1
Aquatic Chronic 1 H400
H410 GHS09
Wng H410 M = 1000
M = 1000 607-743-00-5 L-(+)-lactic acid;
(2S)-2-hydroxypropanoic acid 201-196-2 79-33-4 Skin Corr. 1C
Eye Dam. 1 H314
H318 GHS05
Dgr H314 EUH071 607-744-00-0 2-methoxyethyl acrylate 221-499-3 3121-61-7 Flam. Liq. 3
Muta. 2
Repr. 1B
Acute Tox. 3
Acute Tox. 4
Skin Corr. 1C
Eye Dam. 1
Skin Sens. 1 H226
H341
H360FD
H331
H302
H314
H318
H317 GHS02
GHS05
GHS06
GHS08
Dgr H226
H341
H360FD
H331
H302
H314
H317 EUH071 inhalation: ATE = 2,7 mg/L (vapours)
oral: ATE = 404 mg/kg bw 607-745-00-6 glyoxylic acid …% 206-058-5 298-12-4 Eye Dam. 1
Skin Sens. 1B H318
H317 GHS05
GHS07
Dgr H318
H317 B
607-746-00-1 sodium N-(hydroxymethyl)glycinate;
[formaldehyde released from sodium N-(hydroxymethyl)glycinate] 274-357-8 70161-44-3 Carc. 1B
Muta. 2
Acute Tox. 4
Acute Tox. 4
STOT SE 3
Skin Irrit. 2
Eye Irrit. 2
Skin Sens. 1 H350
H341
H332
H302
H335
H315
H319
H317 GHS08
GHS07
Dgr H350
H341
H332
H302
H335
H315
H319
H317 inhalation: ATE = 3 mg/L (dusts or mists)
oral: ATE = 1100 mg/kg bw 8
9
608-001-00-3 acetonitrile; cyanomethane 200-835-2 75-05-8 Flam. Liq. 2
Acute Tox. 4 * Acute Tox. 4 * Acute Tox. 4 *
Eye Irrit. 2 H225
H332
… 1,097 unchanged lines …
Dgr H350
H360D *** H302
H410 609-041-00-4 2,4-dinitrophenol 200-087-7 51-28-5 Acute Tox. 3 *
Acute Tox. 3 *
Acute Tox. 3 *
STOT RE 2 * Acute Tox. 3
Acute Tox. 2
STOT RE 1
Aquatic Acute 1 H331
H311
H301
H373 ** H300
H372
H400 GHS06
GHS08
GHS09
Dgr H331
H311
H301
H373 **
H400 609-042-00-X pendimethalin (ISO); H300
H372
H400 dermal: ATE = 300 mg/kg bw oral: ATE = 30 mg/kg bw 609-042-00-X pendimethalin (ISO);
N-(1-ethylpropyl)-2,6-dinitro-3,4-xylidine 254-938-2 40487-42-1 Skin Sens. 1
Aquatic Acute 1
Aquatic Chronic 1 H317
… 314 unchanged lines …
H411 GHS07
GHS09
Wng H302
H411 609-064-00-X mesotrione(ISO);
2-[4-(methylsulfonyl)-2-nitrobenzoyl]-1,3-cyclohexanedione — 104206-82-8 Aquatic Acute 1
Aquatic Chronic 1 H400
H410 GHS09
Wng H410 609-065-00-5 2-nitrotoluene 201-853-3 88-72-2 Carc. 1B H411 609-064-00-X mesotrione (ISO);
2-[4-(methylsulfonyl)-2-nitrobenzoyl]-1,3-cyclohexanedione - 104206-82-8 Repr. 2
STOT RE 2
Aquatic Acute 1
Aquatic Chronic 1 H361d
H373 (eyes, nervous system)
H400
H410 GHS08
GHS09
Wng H361d
H373 (eyes, nervous system)
H410 M = 10
M = 10 609-065-00-5 2-nitrotoluene 201-853-3 88-72-2 Carc. 1B
Muta. 1B
Repr. 2
Acute Tox. 4 *
… 1,071 unchanged lines …
GHS07
Dgr H318
H317 611-180-00-0 iron, complexes with diazotised
4-aminobenzenesulfonamide, diazotized 3-aminobenzenesulfonic acid, diazotised 3-amino-4-hydroxybenzenesulfonamide, diazotised 3-amino-4-hydroxy-N-phenylbenzenesulfonamide, diazotised 5-amino-2-(phenylamino)benzenesulfonic acid and resorcinol, sodium salts 417-850-7 — Aquatic Chronic 2 H411 GHS09 H411 612-001-00-9 mono-methylamine; [1] 4-aminobenzenesulfonamide, diazotized 3-aminobenzenesulfonic acid, diazotised 3-amino-4-hydroxybenzenesulfonamide, diazotised 3-amino-4-hydroxy-N-phenylbenzenesulfonamide, diazotised 5-amino-2-(phenylamino)benzenesulfonic acid and resorcinol, sodium salts 417-850-7 — Aquatic Chronic 2 H411 GHS09 H411 611-181-00-6 potassium (oxido-NNO-azoxy)cyclohexane;
cyclohexylhydroxydiazene 1-oxide, potassium salt;
[K-HDO] - 66603-10-9 Flam. Sol. 1
Acute Tox. 3
STOT RE 2
Skin Irrit. 2
Eye Dam. 1
Aquatic Chronic 2 H228
H301
H373 (liver)
H315
H318
H411 GHS02
GHS06
GHS08
GHS05
GHS09
Dgr H228
H301
H373 (liver)
H315
H318
H411 oral: ATE = 136 mg/kg bw 612-001-00-9 mono-methylamine; [1]
di-methylamine; [2]
tri-methylamine [3] 200-820-0 [1]
204-697-4 [2]
… 3,542 unchanged lines …
GHS05
Dgr H361f
H302
H314 EUH071 613-001-00-1 ethyleneimine; aziridine 205-793-9 151-56-4 Flam. Liq. 2 H314 EUH071 612-294-00-3 mecetronium etilsulfate;
N-ethyl-N,N-dimethylhexadecan-1-aminium ethyl sulfate;
mecetronium ethyl sulphate;
[MES] 221-106-5 3006-10-8 Skin Corr. 1
Eye Dam. 1
Aquatic Acute 1
Aquatic Chronic 1 H314
H318
H400
H410 GHS05
GHS09
Dgr H314
H410 EUH071 M = 100
M = 1000 613-001-00-1 ethyleneimine; aziridine 205-793-9 151-56-4 Flam. Liq. 2
Carc. 1B
Muta. 1B
Acute Tox. 2 *
… 1,044 unchanged lines …
H319 GHS08
GHS07
Wng H361d *** H302
H319 613-112-00-5 octhilinone (ISO);2-octyl-2H-isothiazol-3-one 247-761-7 26530-20-1 Acute Tox. 3 *
Acute Tox. 3 *
Acute Tox. 4 *
Skin Corr. 1B
Skin Sens. 1
Aquatic Acute 1
Aquatic Chronic 1 H331 H319 613-112-00-5 octhilinone (ISO);
2-octyl-2H-isothiazol-3-one; [OIT] 247-761-7 26530-20-1 Acute Tox. 2
Acute Tox. 3
Acute Tox. 3
Skin Corr. 1
Eye Dam. 1
Skin Sens. 1A
Aquatic Acute 1 Aquatic Chronic 1 H330
H311
H302 H301
H314
H318
H317
H400
H410 GHS06
GHS05
GHS09
Dgr H331 Dgr H330
H311
H302 H301
H314
H317
H410 Skin Sens. 1; H317: C≥0,05 % 613-113-00-0 2-(morpholinothio)benzothiazole 203-052-4 102-77-2 Eye Irrit. 2 H410 EUH071 inhalation: ATE = 0,27 mg/L (dusts or mists)
dermal: ATE = 311 mg/kg bw oral: ATE = 125 mg/kg bw
Skin Sens. 1A; H317: C ≥ 0,0015 %
M = 100
M = 100 613-113-00-0 2-(morpholinothio)benzothiazole 203-052-4 102-77-2 Eye Irrit. 2
Skin Irrit. 2
Skin Sens. 1
Aquatic Chronic 2 H319
H315
H317
H411 GHS07
GHS09
Wng H319
H315
H317
H411 613-114-00-6 2,2',2''-(hexahydro-1,3,5- triazine-1,3,5-triyl)triethanol;1,3,5-tris(2-hydroxyethyl)hexahydro-1,3,5-triazine 225-208-0 4719-04-4 Acute Tox. 4 *
Skin Sens. 1 H302
H317 GHS07
Wng H302
H317 Skin Sens. 1; H317: C ≥
0,1 % 613-115-00-1 hymexazol (ISO);3-hydroxy-5-methylisoxazole 233-000-6 10004-44-1 Acute Tox. 4 * 0,1 % 613-115-00-1 hymexazol (ISO);
3-hydroxy-5-methylisoxazole 233-000-6 10004-44-1 Repr. 2
Acute Tox. 4
Eye Dam. 1
Aquatic Chronic 3 H302 Skin Sens. 1
Aquatic Chronic 2 H361d
H302
H318
H412 GHS05 H317
H411 GHS08
GHS07
Dgr H302 GHS05
GHS09
Dgr H361d
H302
H318
H412 613-116-00-7 tolylfluanid (ISO);dichloro-N-[(dimethylamino)sulphonyl]fluoro-N-(p-tolyl)methanesulphenamide;[containing ≥0.1 % (w/w) of particles with an aerodynamic diameter of below 50 μm] 211-986-9 731-27-1 Acute Tox. 2 * STOT RE 1 H317
H411 oral: ATE = 1600 mg/kg bw 613-116-00-7 tolylfluanid (ISO);dichloro-N-[(dimethylamino)sulphonyl]fluoro-N-(p-tolyl)methanesulphenamide;[containing ≥0.1 % (w/w) of particles with an aerodynamic diameter of below 50 μm] 211-986-9 731-27-1 Acute Tox. 2 * STOT RE 1
Eye Irrit. 2
STOT SE 3
Skin Irrit. 2
… 83 unchanged lines …
GHS09
Wng H361d *** H302
H315
H411 613-125-00-6 hexythiazox(ISO);trans-5-(4-chlorophenyl)-N- cyclohexyl-4-methyl-2-oxo-3-thiazolidine-carboxamide — 78587-05-0 Aquatic Acute 1 H411 613-125-00-6 hexythiazox (ISO);
trans-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-3-thiazolidine-carboxamide - 78587-05-0 Aquatic Acute 1
Aquatic Chronic 1 H400
H410 GHS09
Wng H410 613-126-00-1 imazapyr (ISO);2-[4,5-dihydro-4-methyl-4-(1- methylethyl)-5-oxo-1H- imidazol-2-yl]-3-pyridine carboxylate — 81334-34-1 Eye Irrit. 2 Wng H410 M = 1
M = 1 613-126-00-1 imazapyr (ISO);2-[4,5-dihydro-4-methyl-4-(1- methylethyl)-5-oxo-1H- imidazol-2-yl]-3-pyridine carboxylate — 81334-34-1 Eye Irrit. 2
Aquatic Chronic 3 H319
H412 GHS07
Wng H319
… 544 unchanged lines …
H302
H317
H410 EUH070 613-202-00-4 pymetrozine (ISO);
(E)-4,5-dihydro-6-methyl-4-(3-pyridylmethyleneamino)-1,2,4-triazin-3(2H)-one — 123312-89-0 Carc. 2
Aquatic Chronic 3 H351
H412 GHS08 (E)-4,5-dihydro-6-methyl-4-(3-pyridylmethyleneamino)-1,2,4-triazin-3(2H)-one - 123312-89-0 Carc. 2
Repr. 2
Aquatic Chronic 1 H351
H361fd
H410 GHS08
GHS09
Wng H351
H412 613-203-00-X pyraflufen-ethyl (ISO); H361fd
H410 M = 1 613-203-00-X pyraflufen-ethyl (ISO);
2-chloro-5-(4-chloro-5-difluoromethoxy-1-methylpyrazol-3-yl)-4-fluorophenoxyacetic acid ethyl ester; [1] pyraflufen (ISO);
2-chloro-5-(4-chloro-5-difluoromethoxy-1-methylpyrazol-3-yl)-4-fluorophenoxyacetic acid [2] -[1]
-[2] 129630-19-9 [1]
… 314 unchanged lines …
Aquatic Chronic 3 H314
H412 GHS05
Dgr H314
H412 613-259-00-5 reaction mass of: [2,4-dioxo-(2-propyn-1-yl)imidazolidin-3-yl]methyl(1R)-cis-chrysanthemate;
[2,4-dioxo-(2-propyn-1-yl)imidazolidin-3-yl]methyl(1R)-trans-chrysanthemate 428-790-6 72963-72-5 Acute Tox. 4 * H412 613-259-00-5 imiprothrin (ISO);
reaction mass of: [2,4-dioxo-(2-propyn-1-yl)imidazolidin-3-yl]methyl(1R)-cis-chrysanthemate; [2,4-dioxo-(2-propyn-1-yl)imidazolidin-3-yl]methyl(1R)-trans-chrysanthemate 428-790-6 72963-72-5 Carc. 2
Acute Tox. 4
Acute Tox. 4
STOT SE 2
Aquatic Acute 1
Aquatic Chronic 1 H302 Aquatic Chronic 1 H351
H332
H302
H371 (nervous system; oral, inhalation)
H400
H410 GHS07 H410 GHS08
GHS07
GHS09
Wng H302
H410 613-260-00-0 (±)-4-(3-chlorophenyl)-6-[(4-chlorophenyl)hydroxy(1-methyl-1H-imidazol-5-yl)methyl]-1-methyl-2(1H)-quinolin 430-730-9 — Eye Dam. 1 Wng H351
H332
H302
H371 (nervous system; oral, inhalation)
H410 inhalation: ATE = 1,4 mg/L (dusts or mists)
oral: ATE = 550 mg/kg bw
M = 10
M = 10 613-260-00-0 (±)-4-(3-chlorophenyl)-6-[(4-chlorophenyl)hydroxy(1-methyl-1H-imidazol-5-yl)methyl]-1-methyl-2(1H)-quinolin 430-730-9 — Eye Dam. 1
Aquatic Acute 1
Aquatic Chronic 1 H318
H400
… 553 unchanged lines …
Dgr H360D
H410 M = 1000
M = 1000 613-330-00-0 2-methylimidazole 211-765-7 693-98-1 Repr. 1B H360Df GHS08
Dgr H360Df 614-001-00-4 nicotine (ISO); Dgr H360Df 613-331-00-6 (2RS)-2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1H-1,2,4-triazol-1-yl)propan-2-ol;
mefentrifluconazole - 1417782-03-6 Skin Sens. 1
Aquatic Acute 1
Aquatic Chronic 1 H317
H400
H410 GHS07
GHS09
Wng H317
H410 M = 1
M = 1 613-332-00-1 oxathiapiprolin (ISO);
1-(4-{4-[5-(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazol-2-yl}piperidin-1-yl)-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]ethanone - 1003318-67-9 Aquatic Chronic 1 H410 GHS09
Wng H410 M = 1 613-333-00-7 pyrithione zinc; (T-4)-bis[1-(hydroxy-.kappa.O)pyridine-2(1H)-thionato-.kappa.S]zinc 236-671-3 13463-41-7 Repr. 1B
Acute Tox. 2
Acute Tox. 3
STOT RE 1
Eye Dam. 1
Aquatic Acute 1
Aquatic Chronic 1 H360D
H330
H301
H372
H318
H400
H410 GHS08
GHS06
GHS05
GHS09
Dgr H360D
H330
H301
H372
H318
H410 inhalation: ATE = 0,14 mg/L (dusts or mists)
oral: ATE = 221 mg/kg bw
M = 1000
M = 10 613-334-00-2 flurochloridone (ISO);
3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one 262-661-3 61213-25-0 Repr. 1B
Acute Tox. 4
Skin Sens. 1
Aquatic Acute 1
Aquatic Chronic 1 H360FD
H302
H317
H400
H410 GHS08
GHS07
GHS09
Dgr H360FD
H302
H317
H410 oral: ATE = 500 mg/kg bw
M = 100
M = 100 613-335-00-8 4,5-dichloro-2-octyl-2H-isothiazol-3-one; [DCOIT] 264-843-8 64359-81-5 Acute Tox. 2
Acute Tox. 4
Skin Corr. 1
Eye Dam. 1
Skin Sens. 1A
Aquatic Acute 1
Aquatic Chronic 1 H330
H302
H314
H318
H317
H400
H410 GHS06
GHS05
GHS09
Dgr H330
H302
H314
H317
H410 EUH071 inhalation: ATE = 0,16 mg/L (dusts or mists)
oral: ATE = 567 mg/kg bw
Skin Irrit. 2; H315: 0,025 % ≤ C < 5 %
Eye Irrit. 2; H319: 0,025 % ≤ C < 3 %
Skin Sens. 1A; H317: C ≥ 0,0015 %
M = 100
M = 100 613-336-00-3 2-methyl-1,2-benzothiazol-3(2H)-one;
[MBIT] - 2527-66-4 Acute Tox. 4
Acute Tox. 3
Skin Corr. 1C
Eye Dam. 1
Skin Sens. 1A
Aquatic Acute 1
Aquatic Chronic 2 H312
H301
H314
H318
H317
H400
H411 GHS06
GHS05
GHS09
Dgr H312
H301
H314
H317
H410 EUH071 dermal: ATE = 1100 mg/kg bw
oral: ATE = 175 mg/kg bw
Skin Sens. 1A; H317: C ≥ 0,0015 %
M = 1 614-001-00-4 nicotine (ISO);
3-[(2S)-1-methylpyrrolidin-2-yl]pyridine 200-193-3 54-11-5 Acute Tox. 2
Acute Tox. 2
Acute Tox. 2
… 823 unchanged lines …
H319 GHS06
Dgr H311
H302
H319 616-014-00-0 2-butanone oxime;
ethyl methyl ketoxime;
ethyl methyl ketone oxime 202-496-6 96-29-7 Carc. 2
Acute Tox. 4 * H319 616-014-00-0 butanone oxime; ethyl methyl ketoxime; ethyl methyl ketone oxime 202-496-6 96-29-7 Carc. 1B
Acute Tox. 4
Acute Tox. 3
STOT SE 3
STOT SE 1
STOT RE 2
Skin Irrit. 2
Eye Dam. 1
Skin Sens. 1 H351 Skin Sens. 1 H350
H312
H301
H336
H370 (upper respiratory tract)
H373 (blood system)
H315
H318
H317 GHS08
GHS06
GHS05
GHS07
Dgr H351 Dgr H350
H312
H301
H336
H370 (upper respiratory tract)
H373 (blood system)
H315
H318
H317 616-015-00-6 alachlor (ISO); H317 dermal: ATE = 1100 mg/kg bw oral: ATE = 100 mg/kg bw 616-015-00-6 alachlor (ISO);
2-chloro-2',6'-diethyl-N-(methoxymethyl)acetanilide 240-110-8 15972-60-8 Carc. 2
Acute Tox. 4 *
Skin Sens. 1
… 1,035 unchanged lines …
H373 GHS08
Wng H361fd
H362
H373 617-001-00-2 di-tert-butyl peroxide 203-733-6 110-05-4 Org. Perox. E Flam. Liq. 2 Muta. 2 H242 H373 616-228-00-4 3-(difluoromethyl)-1-methyl-N-(3',4',5'-trifluorobiphenyl-2-yl)pyrazole-4-carboxamide;
fluxapyroxad - 907204-31-3 Lact.
Aquatic Acute 1
Aquatic Chronic 1 H362
H400
H410 GHS09
Wng H362
H410 M = 1
M = 1 616-230-00-5 N-(hydroxymethyl)acrylamide; methylolacrylamide; [NMA] 213-103-2 924-42-5 Carc. 1B
Muta. 1B
STOT RE 1 H350
H340
H372 (peripheral nervous system) GHS08
Dgr H350
H340
H372 (peripheral nervous system) 616-231-00-0 5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide; 2'-[(RS)-1,3-dimethylbutyl]-5-fluoro-1,3-dimethylpyrazole-4-carboxanilide;
penflufen - 494793-67-8 Carc. 2
Aquatic Acute 1
Aquatic Chronic 1 H351
H400
H410 GHS08
GHS09
Wng H351
H410 M = 1
M = 1 616-232-00-6 iprovalicarb (ISO);
isopropyl [(2S)-3-methyl-1-{[1-(4-methylphenyl)ethyl]amino}-1-oxobutan-2-yl]carbamate - 140923-17-7 Carc. 2 H351 GHS08
Wng H351 616-233-00-1 silthiofam (ISO);
N-allyl-4,5-dimethyl-2-(trimethylsilyl)thiophene-3-carboxamide - 175217-20-6 STOT RE 2
Aquatic Chronic 2 H373
H411 GHS08
GHS09
Wng H373
H411 617-001-00-2 di-tert-butyl peroxide 203-733-6 110-05-4 Org. Perox. E Flam. Liq. 2 Muta. 2 H242
H225
H341 GHS02
GHS08
… 45 unchanged lines …
Dgr H242
H302
H314
H410 STOT SE 3; H335: C ≥ 5 % 617-006-00-X bis(α, α-dimethylbenzyl)
peroxide 201-279-3 80-43-3 Org. Perox. F H410 STOT SE 3; H335: C ≥ 5 % 617-006-00-X bis(α,α-dimethylbenzyl) peroxide 201-279-3 80-43-3 Org. Perox. F
Repr. 1B
Skin Irrit. 2
Eye Irrit. 2
Skin Irrit. 2
Aquatic Chronic 2 H242
H360D
H315
H319
H315
H411 GHS02
GHS08
GHS07
GHS09
Wng H242 Dgr H242
H360D
H315
H319
H315
H411 617-007-00-5 tert-butyl α, α-dimethylbenzyl peroxide 222-389-8 3457-61-2 Org. Perox. E
Skin Irrit. 2
Aquatic Chronic 2 H242
… 5,136 unchanged lines …
STOT RE 1 H360FD
H372 (immune system) GHS08
Dgr H360FD
H372 (immune system) Table 3.2 H372 (immune system) 650-057-00-6 Margosa, ext. [cold-pressed oil of Azadirachta indica seeds without shells extracted with super-critical carbon dioxide] 283-644-7 84696-25-3 Aquatic Chronic 3 H412 H412 Table 3.2
The list of harmonised classification and labelling of hazardous substances from Annex I to Directive 67/548/EEC
Index No International Chemical Identification EC No CAS No Classification Labelling Concentration Limits Notes
001-001-00-9 hydrogen 215-605-7 1333-74-0 F+; R12 F+
… 19,751 unchanged lines …
S: 61 650-055-00-5 silver sodium zirconium hydrogenphosphate 422-570-3 155925-27-2 N; R50-53 N
R: 50/53
S: 60-61
The full entry, with the citation mapping v1 = 02008R1272-20211001, v2 = 02008R1272-20220301, is committed at eu/32008R1272/CHANGELOG.md.